Both general and abdominal adiposity are stroke risk predictors in Chinese women
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The associations between both general and abdominal adiposity and stroke are not well characterized, particularly in populations with different anthropometrics, such as the often leaner Asian populations. This prospective cohort study of Chinese women aged 40 to 70 years participating in the Shanghai Women’s Health Study evaluated the associations between body mass index (BMI; a general obesity estimate), waist-to-hip ratio (WHR), waist circumference (WC), and waist-to-height ratio (WHtR; the latter three as central adiposity estimators) and stroke risk. A total of 67,083 women with no prior history of stroke, coronary heart disease, rheumatic heart disease, cardiac surgery, or cancer at recruitment were included in the analysis. Among this cohort, the cut-points for the highest quintile were: BMI 26.6 kg/m2; WHR 0.85; WC 84.1 cm, and WHtR 0.54. A total of 2403 incident stroke cases were observed during the 7.3-year follow-up period. All selected anthropometric measurements were positively, significantly, and dose-dependently associated with risk of total, ischaemic, and haemorrhagic stroke.
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