Psychosocial deprivation as an independent determinant of metabolic syndrome in a Paris suburb
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A total of 17,074 subjects attending the Health Examination Centre of a northern suburb of Paris participated in this study designed to examine the relationship between metabolic syndrome (NCEP ATP III definition) and psychosocial deprivation. Patients with known diabetes and current lipid-lowering treatment were not included. The Evaluation of Deprivation and Inequalities by Health Examination Centres (EPICES) score was used to analyze social deprivation. The prevalence of metabolic syndrome was significantly (P<0.0001) higher in the deprived group, for every age group. Except for blood glucose, the prevalence of metabolic syndrome components in this nondiabetic population was also significantly higher in the deprived group. In non-obese subjects, the deprivation rate increased with the number of metabolic syndrome components. Multiple regression analysis revealed that female gender, age and deprivation were independent predictors of metabolic syndrome. On separate analysis of the obese and non-obese populations, deprivation remained an independent predictor of metabolic syndrome only in the non-obese. In conclusion, psychosocial deprivation appears to be an independent predictor of metabolic syndrome in non-obese subjects, with elderly psychosocially deprived women being at a particularly high risk.
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